Deoxyribonuclease II

Updated on Sep 30, 2024

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Symbol DNASE2 HUGO 2960 RefSeq NM_001375		Entrez 1777 OMIM 126350

Alt. symbols DNASE2A, DRN2, DNL, DNL2

Gene music using protein sequence of dnase2b deoxyribonuclease ii beta

Deoxyribonuclease II (EC 3.1.22.1, DNase II, pancreatic DNase II, deoxyribonucleate 3'-nucleotidohydrolase, pancreatic DNase II, acid deoxyribonuclease, acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA, yielding products with 3'-phosphates. As the name implies, it is more effective at acid pH.

There are several known DNases II, including:

DNase II alpha (usually just called DNase II)

DNase II beta (also called DLAD, or DNase II-Like Acid DNase)

References

Deoxyribonuclease II Wikipedia

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