Girish Mahajan (Editor)

Deoxyribonuclease II

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Symbol
  
DNASE2

HUGO
  
2960

RefSeq
  
NM_001375

Entrez
  
1777

OMIM
  
126350

Deoxyribonuclease II destaticcloudclonecomitemimgDeoxyribonuclea

Alt. symbols
  
DNASE2A, DRN2, DNL, DNL2

Gene music using protein sequence of dnase2b deoxyribonuclease ii beta


Deoxyribonuclease II (EC 3.1.22.1, DNase II, pancreatic DNase II, deoxyribonucleate 3'-nucleotidohydrolase, pancreatic DNase II, acid deoxyribonuclease, acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA, yielding products with 3'-phosphates. As the name implies, it is more effective at acid pH.

There are several known DNases II, including:

  • DNase II alpha (usually just called DNase II)
  • DNase II beta (also called DLAD, or DNase II-Like Acid DNase)

    • References

    Deoxyribonuclease II Wikipedia
    (Text) CC BY-SA