|EC number 188.8.131.52|
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|CAS number 101920-83-6|
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KEGG KEGG entry
In enzymology, a deoxyhypusine monooxygenase (EC 184.108.40.206) is an enzyme that catalyzes the chemical reactionprotein N6-(4-aminobutyl)-L-lysine + AH2 + O2
The 3 substrates of this enzyme are a protein-bound N6-(4-aminobutyl)-L-lysine, an electron acceptor AH2, and O2, and its 3 products are protein-bound N6-[(R)-4-amino-2-hydroxybutyl]-L-lysine, the reduction product A, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating). Other names in common use include deoxyhypusine hydroxylase, and deoxyhypusine dioxygenase.