Neha Patil (Editor)

Deoxyhypusine monooxygenase

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EC number  1.14.99.29
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  101920-83-6
BRENDA  BRENDA entry
KEGG  KEGG entry

In enzymology, a deoxyhypusine monooxygenase (EC 1.14.99.29) is an enzyme that catalyzes the chemical reaction

protein N6-(4-aminobutyl)-L-lysine + AH2 + O2 protein N6-[(R)-4-amino-2-hydroxybutyl]-L-lysine + A + H2O

The 3 substrates of this enzyme are a protein-bound N6-(4-aminobutyl)-L-lysine, an electron acceptor AH2, and O2, and its 3 products are protein-bound N6-[(R)-4-amino-2-hydroxybutyl]-L-lysine, the reduction product A, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating). Other names in common use include deoxyhypusine hydroxylase, and deoxyhypusine dioxygenase.

References

Deoxyhypusine monooxygenase Wikipedia


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