Rahul Sharma (Editor)

Deoxyadenosine kinase

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EC number
  
2.7.1.76

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37278-12-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a deoxyadenosine kinase (EC 2.7.1.76) is an enzyme that catalyzes the chemical reaction

ATP + deoxyadenosine ADP + dAMP

Thus, the two substrates of this enzyme are ATP and deoxyadenosine, whereas its two products are ADP and dAMP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:deoxyadenosine 5'-phosphotransferase. This enzyme is also called purine-deoxyribonucleoside kinase. This enzyme participates in purine metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2JAQ.

References

Deoxyadenosine kinase Wikipedia