EC number 2.7.1.76 ExPASy NiceZyme view | CAS number 37278-12-9 | |
In enzymology, a deoxyadenosine kinase (EC 2.7.1.76) is an enzyme that catalyzes the chemical reaction
ATP + deoxyadenosine
Thus, the two substrates of this enzyme are ATP and deoxyadenosine, whereas its two products are ADP and dAMP.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:deoxyadenosine 5'-phosphotransferase. This enzyme is also called purine-deoxyribonucleoside kinase. This enzyme participates in purine metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2JAQ.
References
Deoxyadenosine kinase Wikipedia(Text) CC BY-SA