Denisе́nko — slavic sourname. Famous representatives:
Oleg Ivanovich Denisenko (born 1962) — Russian politician. State Duma Deputy (CPRF).
Pyotr Ivanovich Denisenko (1920–1998) — soviet athlete and a coach.
Sergey Petrovich Denisenko (1921–1961) — Soviet Union's hero.
Stephan Petrovich Denisenko (1916–2000) — veteran and a sniper-hero of World War II, full Cavalier of the Order of Glory.
Filaret (Denisenko) (born 1929) — the head of the Ukrainian Orthodox Church and a Patriarch of the Ukraine.
Maxim Denisenko (1929–1993) — literary pseudonym of the writer Nikolai Glukhenky.