Samiksha Jaiswal (Editor)

Decoglurant

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ATC code
  
none

CAS Number
  
911115-16-7

ChemSpider
  
32695160

Formula
  
C21H11F6N5

Legal status
  
Development terminated

PubChem CID
  
71533696

3D model (Jmol)
  
Interactive image

Molar mass
  
447.336 g/mol

Decoglurant httpsuploadwikimediaorgwikipediacommonsthu

Decoglurant (INN) (code name RG1578, RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors which was under development by Roche for the adjunctive treatment of major depressive disorder. Decoglurant progressed as far as phase II clinical trials but was ultimately discontinued from further development due to disappointing efficacy results.

References

Decoglurant Wikipedia