DeMille or De Mille is a surname. Notable people with the surname include:
Agnes De Mille, American dancer/choreographer
Cecil B. DeMille, American film director
Constance Adams DeMille, Actress
Evelyn de Mille (1919–2013), Canadian bookseller
James De Mille, Canadian writer
Katherine DeMille, Actress
Nelson DeMille, American author
Oliver DeMille, American author and educator
Richard de Mille, Journalist and author
William C. deMille, American screenwriter and film director
