DeLuca, Deluca or De Luca may refer to:
People
Adrian Deluca (born 1982), former Australian rules footballer
Anthony DeLuca (disambiguation), various people
Frank Deluca (1898-1967), Italian-American mobster and brother of Joseph DeLuca
Fred DeLuca (1948-2015), American businessman and co-founder of the Subway franchise of sandwich restaurants
George DeLuca (1889-1983), American lawyer, banker and politician
Giorgio DeLuca, businessman and a founder of the gourmet grocery store Dean & DeLuca
Giuseppe De Luca (1876–1950), Italian baritone
Hector DeLuca, American biochemist and professor
Joseph Deluca (1893-1952), Italian-American mobster
Louis DeLuca (born 1933), American retired businessman and politician; former Connecticut state senator
Nick De Luca (born 1984), Scottish rugby union player
Rob De Luca, American rock bass guitarist
Rocco DeLuca (born 1975), leader and guitarist of the now-disbanded indie rock band Rocco DeLuca and the Burden
Sam DeLuca (1936-2011), American Football League lineman
Fictional characters
Maria DeLuca, fictional character in Melinda Metz's young adults book series Roswell High and the TV series Roswell
Detective Achille De Luca from Inspector De Luca, an Italian TV police drama set during Mussolini's reign, based on the novel series of the same name of Carlo Lucarelli
