de Wit is a surname of Dutch origin related to de Witt. People with the name include:
Bernard de Wit (contemporary), Dutch theoretical physicist
Caitlin De Wit (born 1987), Australian wheelchair basketball player
Frederik de Wit, three members of a 17th-century family of family Dutch engravers, cartographers, and publishers
Hendrik de Wit (1909–1999), Dutch botanist
Jacob de Wit (1695–1754), Dutch painter
Jan de Wit (born 1945), Dutch lawyer and politician
Maarten de Wit (1883–1955), Dutch Olympic sailor
Michaël Dudok de Wit (born 1953), Dutch animator, film director, and illustrator
Pierre de Wit (born 1987), German professional football player
Rob de Wit (athlete) (born 1962), Dutch decathlete and bobsledder
Rob de Wit (footballer) (born 1963), Dutch professional football player
Robert de Wit (born 1962), Dutch Olympic decathlete
Willie de Wit (born 1961), Canadian lawyer, and Olympic and professional boxer
Yannick de Wit (born 1986), Dutch professional football player
Alex de Wit (born 2000), Canadian bassoonist