de Martino or DeMartino is an Italian surname. Notable people with the surname include:
Giovanni de Martino (1870–1935), Italian sculptor
Alberto De Martino (1929–2015), Italian film director and screenwriter
Angelo de Martino, Italian cyclist
Antonio De Martino (1815–1904), Italian physician, researcher and politician
Edoardo De Martino, Italian painter
Ernesto de Martino (1908–1965), Italian philosopher and anthropologist
Francesco De Martino (1907–2002), Italian politician
Giacomo De Martino, (1868-1957) Italian diplomat.
Giacomo De Martino (1849-1921) colonial administrator.
Jules De Martino (born 1969), British musician
Nick DeMartino (born 1948), American businessman
Raffaele De Martino (born 1986), Italian footballer
Richard DeMartino, American bridge player
Tino DeMartino, Belgian musician
