De Man is a Dutch surname, meaning "the man". People with this surname include:
Cornelis de Man (1621–1706), Dutch Golden Age painter
Filip De Man (born 1955), Belgian politician and journalist
de:Harald de Man (born 1973), Dutch skier
Hendrik de Man, also known as Henri de Man (1885–1953), Belgian politician
Herman de Man (1898–1946), Dutch novelist
Johannes Govertus de Man (1850–1930), Dutch biologist
Joris de Man, Dutch video game composer and sound designer
Mark De Man (born 1983), Belgian footballer
Paul de Man (1919–1983), Belgian literary critic
de:Roderik de Man (born 1941), Dutch composer
Roelof de Man (1634–1663), Dutch administrator of the Cape Colony
