De Carolis is the surname of the following people
Adolfo de Carolis (1874–1928), Italian painter, xylographer, illustrator and photographer
Bob De Carolis (born c. 1952), American athletic administrator and softball coach
Giovanni De Carolis (born 1984), Italian professional boxer
Natale de Carolis (born 1957), Italian opera singer
Patrick de Carolis (born 1953), French TV journalist and writer
Ugo de Carolis (1887–1941), Italian military officer
