De Carolis is the surname of the following people
Adolfo de Carolis (1874–1928), Italian painter, xylographer, illustrator and photographerBob De Carolis (born c. 1952), American athletic administrator and softball coachGiovanni De Carolis (born 1984), Italian professional boxerNatale de Carolis (born 1957), Italian opera singerPatrick de Carolis (born 1953), French TV journalist and writerUgo de Carolis (1887–1941), Italian military officer