de Burgh is a surname. Notable people with the surname include:
Chris de Burgh (born 1948), musician and songwriter
Edmond Albanach de Burgh (d. 1375), Lord of Connaught
Elizabeth de Burgh (c. 1289-1327), Scottish royal consort
Elizabeth de Burgh, 4th Countess of Ulster (1332-1363), Earl in the Peerage of Ireland
Ernest Macartney de Burgh (1863-1929), Irish-born Australian civil engineer
Hubert de Burgh, 1st Earl of Kent (c. 1180-1243), Justiciar of England and Ireland
Hubert de Burgh (cricketer) (1879-1960), Irish cricketer and Royal Naval Officer
Hugo de Burgh (21st century), British journalism theorist and academic
John de Burgh (1286–1313) (1286-1313), Irish murder victim
John de Burgh, 13th Earl of Clanricarde (1744-1808), Irish nobleman and politician
John Thomas de Burgh (1744-1808), English cricketer
Jon de Burgh Miller (21st century), English science fiction writer
Richard Mor de Burgh (c. 1194-1242), eldest son of William de Burgh
Richard Óg de Burgh, 2nd Earl of Ulster (1259-1326)
Thomas de Burgh (1670–1730), Irish soldier, architect and politician
Ulick de Burgh, 1st Marquess of Clanricarde (1802-1874), British Whig politician
Walter de Burgh, 1st Earl of Ulster (c. 1230-1271), founder of Athassel Priory
William de Burgh (1157-1206), Lord of Connaught
William Donn de Burgh, 3rd Earl of Ulster (1312-1333), noble in the Peerage of Ireland
William Og de Burgh (died 1270), Irish chieftain
William de Burgh (MP) (1741–1808), Irish theologian, politician and anti-slavery campaigner