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David Hershel Alpers (born 9 May 1935, Philadelphia) is a gastroenterologist and former president of the American Gastroenterological Association (1990–1991).
Dr. Alpers was Chief of the Gastroenterology Division at Washington University School of Medicine from 1969 to 1997 and is currently the William B. Kountz Professor of Medicine and assistant director of the Center for Human Nutrition. He received his M.D. from Harvard Medical School in 1960 and completed training in internal medicine at Massachusetts General Hospital (MGH). He studied molecular biology at the NIH under Gordon Tomkins (1962-64) before returning to MGH for gastroenterology fellowship (1964-66) and junior faculty positions (1966-69). Since moving to Washington University as division chief, he has been Professor of Medicine since 1973. Dr. Alpers is an active participant in the national focus of gastroenterology, served as the president of the American Gastroenterological Association and received the Friedenwald Medal from that association, the most prestigious recognition for a career of scientific contribution to the field.
Dr. Alpers is widely recognized for his research in intestinal protein biochemistry. His efforts are also responsible for much of our knowledge of cobalamin metabolism and absorption by the gastrointestinal tract. His contributions to understanding gut physiology have been so important, his knowledge of the field so great that he was selected as editor of the American Journal of Physiology (Gastrointestinal and Liver Physiology). Dr. Alpers is also recognized for his clinical discoveries. His longstanding interests in the psychiatric aspects of gastrointestinal disease helped formulate some of the current thinking about brain-gut interactions.
He is a world-class expert in neurogastroenterology.