Routes ofadministration Oral Legal status Investigational Biological half-life 12.5 hours Molar mass 410.42 g/mol | ATC code none Metabolism CAS Number 171714-84-4 | |
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Darusentan (LU-135252; HMR-4005) is an endothelin receptor antagonist. Gilead Colorado, a subsidiary of Gilead Sciences, under license from Abbott Laboratories, is developing darusentan for the potential treatment of uncontrolled hypertension.
In June 2003, Myogen licensed the compound from Abbott for its application in the cancer field.
In May 2007, a randomized, double-blind, active control, parallel assignment, safety and efficacy phase III trial was initiated in subjects who had completed the maintenance period of the DAR-312 study.
References
Darusentan Wikipedia(Text) CC BY-SA