Aliases DYRK2 Ensembl ENSG00000127334 | Entrez 8445 | |
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External IDs MGI: 1330301 HomoloGene: 48437 GeneCards: DYRK2 |
Dual specificity tyrosine-phosphorylation-regulated kinase 2 is an enzyme that in humans is encoded by the DYRK2 gene.
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.
References
DYRK2 Wikipedia(Text) CC BY-SA