DTDP 4 amino 4,6 dideoxy D glucose transaminase

In enzymology, a dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (EC 2.6.1.33) is an enzyme that catalyzes the chemical reaction

dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate ⇌ dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate

Thus, the two substrates of this enzyme are dTDP-4-amino-4,6-dideoxy-D-glucose and 2-oxoglutarate, whereas its two products are dTDP-4-dehydro-6-deoxy-D-glucose and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase. Other names in common use include thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase, thymidine diphospho-4-amino-6-deoxyglucose aminotransferase, thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase, thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase, and TDP-4-keto-6-deoxy-D-glucose transaminase. This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, pyridoxal phosphate.