Entrez 1807 | Ensembl ENSG00000147647 | |
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Aliases DPYS, dihydropyrimidinase, DHP, DHPase External IDs MGI: 1928679 HomoloGene: 20359 GeneCards: DPYS | ||
Dihydropyrimidinase is an enzyme that in humans is encoded by the DPYS gene.
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
References
DPYS Wikipedia(Text) CC BY-SA