Supriya Ghosh (Editor)

DPP9

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Species
  
Entrez
  
91039

Human
  
Ensembl
  
ENSG00000142002

Aliases
  
DPP9, DP9, DPLP9, DPRP-2, DPRP2, dipeptidyl peptidase 9

External IDs
  
MGI: 2443967 HomoloGene: 16385 GeneCards: DPP9

Dipeptidyl peptidase 9 is an enzyme that in humans is encoded by the DPP9 gene.

This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.

References

DPP9 Wikipedia


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