Entrez 91039 | Ensembl ENSG00000142002 | |
Aliases DPP9, DP9, DPLP9, DPRP-2, DPRP2, dipeptidyl peptidase 9 External IDs MGI: 2443967 HomoloGene: 16385 GeneCards: DPP9 |
Dipeptidyl peptidase 9 is an enzyme that in humans is encoded by the DPP9 gene.
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.
References
DPP9 Wikipedia(Text) CC BY-SA