Puneet Varma (Editor)

DPF2

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Species
  
Entrez
  
5977

Human
  
Ensembl
  
ENSG00000133884

DPF2

Aliases
  
DPF2, REQ, UBID4, ubi-d4, double PHD fingers 2

External IDs
  
MGI: 109529 HomoloGene: 21265 GeneCards: DPF2

Zinc finger protein ubi-d4 is a protein that in humans is encoded by the DPF2 gene.

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.

References

DPF2 Wikipedia


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