Species Human Entrez 1776 | Human Mouse Ensembl ENSG00000163687 | |
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Aliases DNASE1L3, DHP2, DNAS1L3, LSD, SLEB16, deoxyribonuclease I like 3 External IDs MGI: 1314633 HomoloGene: 3630 GeneCards: DNASE1L3 | ||
Deoxyribonuclease gamma is an enzyme that in humans is encoded by the DNASE1L3 gene.
This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Homozygosity for a null allele results in systemic lupus erythematosus.
References
DNASE1L3 Wikipedia(Text) CC BY-SA