Species Human Entrez 1607 | Human Mouse Ensembl ENSG00000136267 | |
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Aliases DGKB, DAGK2, DGK, DGK-BETA, diacylglycerol kinase beta External IDs MGI: 2442474 HomoloGene: 37875 GeneCards: DGKB | ||
Diacylglycerol kinase beta is an enzyme that in humans is encoded by the DGKB gene.
Function
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.
References
DGKB Wikipedia(Text) CC BY-SA