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D threo aldose 1 dehydrogenase

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EC number
  
1.1.1.122

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9082-70-6

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a D-threo-aldose 1-dehydrogenase (EC 1.1.1.122) is an enzyme that catalyzes the chemical reaction

a D-threo-aldose + NAD+ a D-threo-aldono-1,5-lactone + NADH + H+

Thus, the two substrates of this enzyme are D-threo-aldose and NAD+, whereas its 3 products are D-threo-aldono-1,5-lactone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-threo-aldose:NAD+ 1-oxidoreductase. Other names in common use include L-fucose dehydrogenase, (2S,3R)-aldose dehydrogenase, dehydrogenase, L-fucose, and L-fucose (D-arabinose) dehydrogenase. This enzyme participates in ascorbate and aldarate metabolism.

References

D-threo-aldose 1-dehydrogenase Wikipedia