D pinitol dehydrogenase

In enzymology, a D-pinitol dehydrogenase (EC 1.1.1.142) is an enzyme that catalyzes the chemical reaction

1D-3-O-methyl-chiro-inositol + NADP⁺ ⇌ 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H⁺

Thus, the two substrates of this enzyme are 1D-3-O-methyl-chiro-inositol and NADP⁺, whereas its 3 products are 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 1D-3-O-methyl-chiro-inositol:NADP⁺ oxidoreductase. This enzyme is also called 5D-5-O-methyl-chiro-inositol:NADP⁺ oxidoreductase.