Trisha Shetty (Editor)

D alanine—(R) lactate ligase

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EC number
  
6.1.2.1

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

D-alanine—(R)-lactate ligase (EC 6.1.2.1, VanA, VanB, VanD) is an enzyme with systematic name D-alanine:(R)-lactate ligase (ADP-forming). This enzyme catalyses the following chemical reaction

D-alanine + (R)-lactate + ATP ⇌ D-alanyl-(R)-lactate + ADP + phosphate

The product of this enzyme can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide.

References

D-alanine—(R)-lactate ligase Wikipedia
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