Neha Patil (Editor)

D 2 hydroxy acid dehydrogenase

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EC number
  
1.1.99.6

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9028-83-5

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a D-2-hydroxy-acid dehydrogenase (EC 1.1.99.6) is an enzyme that catalyzes the chemical reaction

(R)-lactate + acceptor pyruvate + reduced acceptor

Thus, the two substrates of this enzyme are (R)-lactate and acceptor, whereas its two products are pyruvate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (R)-2-hydroxy-acid:acceptor 2-oxidoreductase. Other names in common use include D-2-hydroxy acid dehydrogenase, and (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase. It has 2 cofactors: FAD, and Zinc.

References

D-2-hydroxy-acid dehydrogenase Wikipedia