Girish Mahajan (Editor)

Cytochrome b5 reductase

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EC number
  
1.6.2.2

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9032-25-1

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Cytochrome b5 reductase

Cytochrome-b5 reductase (also known as methemoglobin reductase) is a NADH-dependent enzyme that converts methemoglobin to hemoglobin. It contains FAD and catalyzes the reaction:

NADH + H+ + 2 ferricytochrome b5 = NAD+ + 2 ferrocytochrome b5

NADH + H+ + 2 ferricytochrome b5 = NAD+ + 2 ferrocytochrome b5

The following four human genes encode cytochrome-b5 reductases:

  • CYB5R1
  • CYB5R2
  • CYB5R3
  • CYB5R4

    • References

    Cytochrome b5 reductase Wikipedia
    (Text) CC BY-SA