Cycloartenol synthase

In enzymology, a cycloartenol synthase (EC 5.4.99.8) is an enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, (S)-2,3-epoxysqualene, and one product, cycloartenol.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is (S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming). Other names in common use include 2,3-epoxysqualene cycloartenol-cyclase, squalene-2,3-epoxide-cycloartenol cyclase, 2,3-epoxysqualene cycloartenol-cyclase, 2,3-epoxysqualene-cycloartenol cyclase, and 2,3-oxidosqualene-cycloartenol cyclase. This enzyme participates in biosynthesis of steroids.