Symbol CCNE2 HUGO 1590 RefSeq NM_057749 | Entrez 9134 OMIM 603775 UniProt O96020 | |
Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27(Kip1) and p21(Cip1). It plays a role in the G1/S portion of the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer.
References
Cyclin E2 Wikipedia(Text) CC BY-SA