Neha Patil (Editor)

Cyclic guanylate specific phosphodiesterase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
3.1.4.52

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
338732-46-0

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Cyclic-guanylate-specific phosphodiesterase (EC 3.1.4.52, cyclic bis(3->5')diguanylate phosphodiesterase, c-di-GMP-specific phosphodiesterase, c-di-GMP phosphodiesterase, phosphodiesterase, phosphodiesterase A1, PDEA1, VieA) is an enzyme with systematic name cyclic bis(3->5')diguanylate 3-guanylylhydrolase. This enzyme catalyses the following chemical reaction

cyclic di-3',5'-guanylate + H2O ⇌ 5'-phosphoguanylyl(3'->5')guanosine

This enzyme requires Mg2+ or Mn2+ for activity. It is inhibited by Ca2+ and Zn2+.

References

Cyclic-guanylate-specific phosphodiesterase Wikipedia
(Text) CC BY-SA