Routes ofadministration Oral CAS Number 3572-80-3 IUPHAR/BPS 1604 Molar mass 271.4 g/mol | ATC code none PubChem CID 19143 ChemSpider 18063 | |
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Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine. This family of opioid drugs is called the benzomorphans or benzazocines. It is a KOR agonist and MOR partial agonist, and also has high affinity for the DOR.
Use
Research into the use of cyclazocine for the treatment of bipolar patients with depression was undertaken by Fink and colleagues (1970). It showed that 8 out of 10 patients experienced moderate improvement.
Research during the 1960s and 1970s into the possible use of cyclazocine for management of pain, and later for assisting treatment of narcotic addiction was severely hampered by the drug's psychotomimetic, dysphoric, and hallucinatory effects.
References
Cyclazocine Wikipedia(Text) CC BY-SA