Coxe is a surname, and may refer to:
Alfred Conkling Coxe, Sr., American federal judge
Alfred Conkling Coxe, Jr., American federal judge
Arthur Cleveland Coxe, American bishop, son of Samuel Hanson Cox
Daniel Coxe, English governor of West Jersey
Henry Octavius Coxe, English scholar
Hopewell Coxe, American politician
Coxe, also known as John Coxe, was an adopted name of Naukane, a 19th-century Hawaiian labourer for the North West and Hudson's Bay Companies
Louis O. Coxe, American poet
Tench Coxe, early American economist and politician
William Coxe, English historian