Cowie is a surname. Notable people with the surname include:
Chris Cowie, Scottish DJ and producerColin Cowie, lifestyle guruDon Cowie (footballer), association football playerGeorge Cowie, Scottish football playerGeorge Cowie (Wisconsin), American politicianHelen Cowie, Professor of Health and Social Care at University of SussexJack Cowie, New Zealand cricketerJames Cowie (Australian settler), mayor of Geelong, VictoriaJames Cowie (artist), Scottish painterJimmy Cowie, Scottish footballerLennox Cowie, Scottish astronomerPeter Cowie, English film historianRichard Kylea Cowie, British musician better known as Wiley (rapper)Thomas Jefferson Cowie, US Navy rear admiralSir Tom Cowie, English businessman