Costunolide synthase

Updated on Dec 18, 2024

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EC number 1.14.13.120 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Costunolide synthase (EC 1.14.13.120) is an enzyme with systematic name germacra-1(10),4,11(13)-trien-12-oate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating). This enzyme catalyses the following chemical reaction

germacra-1(10),4,11(13)-trien-12-oate + NADPH + H⁺ + O₂ ⇌ (+)-costunolide + NADP⁺ + 2 H₂O

Costunolide synthase is a heme-thiolate protein (P-450).

References

Costunolide synthase Wikipedia

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