The Cosmopolitan Club in London, England, was a club which existed from 1852 to 1902. It met in rooms in Berkeley Square which had previously been the studio of George Frederic Watts and then of Henry Wyndham Phillips. The meeting room was dominated by a large painting by Watts of a naked damsel in distress. The painting, A Story from Boccaccio, depicted the woman fleeing towards a group of classically dressed figures. It was presented to the nation when the club closed.
The membership included literary men, artists, civil servants and political figures. Watts joined, as did the writers Matthew James Higgins (Jacob Omnium), Francis Turner Palgrave, Edward Fitzgerald and Anthony Trollope. Other members included Henry Layard, Sir Robert Morier, James Spedding and William Gladstone.
The club is said to be the basis of "The Universe", "the club where the best informed political gossip is heard", in Trollope's novel Phineas Redux.