Corydaline synthase

In enzymology, a corydaline synthase (EC 2.1.1.147) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + palmatine + 2 NADPH + H⁺ ⇌ S-adenosyl-L-homocysteine + corydaline + 2 NADP⁺

The 4 substrates of this enzyme are S-adenosyl methionine, palmatine, NADPH, and H⁺, whereas its 3 products are S-adenosylhomocysteine, corydaline, and NADP⁺.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase.