Rahul Sharma (Editor)

Corticorelin

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ATC code
  
V04CD04 (WHO)

PubChem CID
  
16132344

Formula
  
C205H339N59O63S

CAS Number
  
79804-71-0

UNII
  
305OE8862Y

Corticorelin

AHFS/Drugs.com
  
International Drug Names

Corticorelin (INN) is a diagnostic agent. It is a synthetic form of human corticotropin-releasing hormone (hCRH).

The corticorelin stimulation test helps to differentiate between the etiologies of adrenocorticotropic hormone (ACTH)-dependent hypercortisolism. It is used to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion.

  • If corticorelin injection increases plasma levels of ACTH and cortisol, a diagnosis of Cushing's disease is achieved (ACTH of pituitary origin).
  • If corticorelin injection leads to little or no response in plasma levels of ACTH or cortisol, a diagnosis of ectopic ACTH syndrome is confirmed.

    • References

    Corticorelin Wikipedia
    (Text) CC BY-SA


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