Colonna is a surname. Notable people with the surname include:
Dominique Colonna (b. 1928), a French former football goalkeeperFrancesco Colonna (1433(?) – 1527) an Italian Dominican monk, the author of Hypnerotomachia PoliphiliGiovanni Colonna (archaeologist) (b. 1934), an Italian scholar of ancient Italy and, in particular, the Etruscan civilization.Giovanni Paolo Colonna (c.1637 – 1695), an Italian musician and composerGuido Colonna di Paliano (1908–1982), an Italian politician and European Commissioner.Jerry Colonna (disambiguation), multiple peopleNiccolò Turrisi Colonna (1817 – 1889), a Sicilian politician from PalermoSarah Colonna, American stand-up comedian, and roundtable regular on Chelsea LatelyVittoria Colonna, 1490–1547, machioness of Pescara, Italian noblewoman, poet, friend of MichelangeloYvan Colonna (b. 1960) a Corsican nationalist