Colonna is a surname. Notable people with the surname include:
Dominique Colonna (b. 1928), a French former football goalkeeper
Francesco Colonna (1433(?) – 1527) an Italian Dominican monk, the author of Hypnerotomachia Poliphili
Giovanni Colonna (archaeologist) (b. 1934), an Italian scholar of ancient Italy and, in particular, the Etruscan civilization.
Giovanni Paolo Colonna (c.1637 – 1695), an Italian musician and composer
Guido Colonna di Paliano (1908–1982), an Italian politician and European Commissioner.
Jerry Colonna (disambiguation), multiple people
Niccolò Turrisi Colonna (1817 – 1889), a Sicilian politician from Palermo
Sarah Colonna, American stand-up comedian, and roundtable regular on Chelsea Lately
Vittoria Colonna, 1490–1547, machioness of Pescara, Italian noblewoman, poet, friend of Michelangelo
Yvan Colonna (b. 1960) a Corsican nationalist
