Entrez 84570 | Ensembl ENSG00000188517 | |
Aliases COL25A1, AMY, CLAC, CLAC-P, CLACP, CFEOM5, Collagen, type XXV, alpha 1, collagen type XXV alpha 1 External IDs MGI: 1924268 HomoloGene: 57111 GeneCards: COL25A1 | ||
Collagen alpha-1(XXV) chain is a protein that in humans is encoded by the COL25A1 gene.
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005).[supplied by OMIM]
Interactions
Collagen, type XXV, alpha 1 has been shown to interact with Amyloid precursor protein.
References
Collagen, type XXV, alpha 1 Wikipedia(Text) CC BY-SA