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Cold nodule is a scintigraphic evidence (hypo functional district / nodes) on the thyroid. The term "cold nodule" refers take the reduced or non-existent capacity of the territory, radioactive ("hot") iodine or technetium. Cold nodes produce little or no hormones triiodothyronine (T3) and thyroxine (T4). To put it differently, cold node is a part of thyroid nodule, not representing in scintigraphy. Figure 1 illustrates the basic anatomy of the thyroid gland. It is easily recognizable by ultrasound (s. Fig. 2 and 3). The case shown in Figure 4 shows a cold nodule quite emphasized representation of the thyroid. The investigation was carried out due to a goiter rating of 3. Striking was the discrepancy between the magnification sonographically depicted the thyroid lobe and the findings in the scintigraphy; the lower part of the right lobe and the lateral part of the left missing in the bone scan, although demonstrably thyroid tissue is present there sonographically. This imperfective representation for thyroid tissue is the characteristic of "cold node".