Coke is a surname. Notable people with the surname include:
Christopher Coke (b. 1969), alleged drug lord in Jamaica
David Coke (1915–1941), a British pilot during World War II
Dorothy Coke (1897-1979), a British artist
Edward Coke (1552–1634), English entrepreneur and jurist
Edward Coke (1758–1837), a British politician and landowner
Edward Coke, 7th Earl of Leicester (1936–2015), a British earl
Giles Coke, an English footballer
John Coke (1563–1644), an English politician
John Talbot Coke (1841-1912), British Army Major-general and author of a Coke family history
Peter Coke (1913–2008), a British actor, playwright and artist
Phil Coke, an American major league baseball pitcher on the Tigers as of 2010-2011
Richard Coke, an American lawyer, farmer, and statesman
Richard Coke, Jr., a Virginia congressman
Richard Toby Coke (born 1954), an English politician
Thomas Coke (bishop) (1747–1814), the first Methodist Bishop
Thomas Coke, 1st Earl of Leicester (seventh creation) (1754–1842), agricultural reformer