Coffey is an Irish surname. Notable people with the surname include:
Prince Oheneba Coffey (born 1984), Ghanaian entrepreneur and consultant
Aeneas Coffey (1780–1852), Irish inventor
Ann Coffey (born 1946), British politician
Brian Coffey (1905–1995), Irish poet
Cath Coffey, British vocalist of Stereo MC's
Charles Coffey (?–1745), Irish playwright
Denise Coffey (born 1936), British actress
Dennis Coffey, American guitarist
George Nelson Coffey (1875−1967), American pedologist
Greg Coffey (born 1971), Australian London-based hedge fund manager
Jack Coffey (baseball) (1887–1966), Major League Baseball player
John Coffey (disambiguation), several people
Kellie Coffey (born 1971), American singer-songwriter
Michael J. Coffey (c.1840–1907), New York politician
Paul Coffey (born 1961), Canadian hockey player
Peter Coffey (1876–1943), Irish Roman Catholic priest and Neoscholastic philosopher
Rich Coffey, American owner of Fort Wayne Freedom, an indoor football team
Russell Coffey (1898–2007), one of the last three surviving American World War I veterans
Sean Coffey (born 1956), New York lawyer
Susanna Coffey, American artist
Tabatha Coffey, Australian hairstylist
Therese Coffey, British Conservative Member of Parliament
Todd Coffey (born 1980), Major League Baseball relief pitcher
Wayne Coffey (journalist), American sportswriter
Wayne Coffey (footballer) (born 1964), American football player
William Coffey (1829–1875), Irish Victoria Cross recipient
William Coffey (cricketer) (born 1885), Irish cricketer