Codeine 3 O demethylase

Updated on Dec 19, 2024

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EC number 1.14.11.32 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Codeine 3-O-demethylase (EC 1.14.11.32, codeine O-demethylase, CODM) is an enzyme with systematic name codeine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating). This enzyme catalyses the following chemical reaction

codeine + 2-oxoglutarate + O₂ ⇌ morphine + formaldehyde + succinate + CO₂

Codeine 3-O-demethylase contains Fe²⁺.

References

Codeine 3-O-demethylase Wikipedia

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