Cobham is a surname. Notable people with the surname include:
Sir Alan Cobham, aviation pioneerAlan Cobham (mathematician), the namesake of the Cobham's thesis in the computational complexity theoryBilly Cobham (born 1944), jazz musicianEleanor Cobham, mistress and later wife of Humphrey, Duke of Gloucester, accused witchEric Cobham, an early 18th-century pirate