Rahul Sharma (Editor)

Cob(II)alamin reductase

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EC number
  
1.16.1.4

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37256-40-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a cob(II)alamin reductase (EC 1.16.1.4) is an enzyme that catalyzes the chemical reaction

2 cob(I)alamin + NAD+ 2 cob(II)alamin + NADH + H+

Thus, the two substrates of this enzyme are cob(I)alamin and NAD+, whereas its 3 products are cob(II)alamin, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those oxidizing metal ion with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cob(I)alamin:NAD+ oxidoreductase. Other names in common use include vitamin B12r reductase, B12r reductase, and NADH2:cob(II)alamin oxidoreductase. This enzyme participates in porphyrin and chlorophyll metabolism. It employs one cofactor, FAD.

References

Cob(II)alamin reductase Wikipedia