Clymer is a surname. Notable people with the surname include:
Adam Clymer, American journalist
Ben Clymer, ice hockey player
Eleanor Clymer, children's author
Floyd Clymer, Pioneer motorcycle racer, dealer, publisher
George Clymer, Signer of Declaration of Independence
George Clymer (inventor), printer and inventor
Hiester Clymer, Pennsylvania politician of the Hiester Family
Jim Clymer, Pennsylvania politician
John Clymer, American artist
John B. Clymer, screenwriter
Mary Willing Clymer, Philadelphia socialite
Paul Clymer, Pennsylvania politician
Otis Clymer, baseball player
Wayne K. Clymer (1917–2013), American United Methodist bishop