Cloughgrenan may refer to:
Baron Butler of Cloughgrenan or Earl of Arran, a title in both the Peerage of Scotland and the Peerage of Ireland
Sir Edmund Butler of Cloughgrenan (1534–1602), second son of James Butler, 9th Earl of Ormond and Lady Joan Fitzgerald
Sir Thomas Butler, 1st Baronet Cloughgrenan (died 1642), Irish nobleman, illegitimate son of Sir Edmund Butler of Cloughgrenan
Sir Thomas Butler, 3rd Baronet Cloughgrenan (died 1704), Irish baronet and politician
Sir Pierce Butler, 4th Baronet Cloughgrenan (1670–1732), Irish politician and baronet
Sir Richard Butler, 5th Baronet Cloughgrenan (1699–1771), Irish politician and baronet
Sir Thomas Butler, 6th Baronet Cloughgrenan (1735–1772), Irish politician and baronet
Sir Richard Butler, 7th Baronet Cloughgrenan (1761–1817), Anglo-Irish politician