ATC code N05AH06 (WHO) Molar mass 343.87 g/mol | CAS Number 2058-52-8 | |
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Trade names Etumina, Etumine, Entumin, Etomine, Entumine AHFS/Drugs.com International Drug Names Routes of
administration Oral, Intravenous and Intramuscular Legal status In general: ℞ (Prescription only) | ||
Clotiapine (Entumine) is an atypical antipsychotic of the dibenzothiazepine chemical class. It was first introduced in a few European countries (namely, Belgium, Italy, Spain and Switzerland), Argentina, Taiwan and Israel in 1970.
Some sources regard clotiapine as a typical antipsychotic rather than atypical due to its high incidence of extrapyramidal side effects compared to the atypicals like clozapine and quetiapine, to which it is structurally related. Despite its profile of a relatively high incidence of extrapyramidal side effects it has demonstrated efficacy in treatment-resistant individuals with schizophrenia according to a number of psychiatrists with clinical experience with it, some weak clinical evidence supports this view too.
References
Clotiapine Wikipedia(Text) CC BY-SA