Clavaminate synthase

Updated on Dec 18, 2024

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EC number 1.14.11.21 IntEnz IntEnz view ExPASy NiceZyme view		CAS number 122799-56-8 BRENDA BRENDA entry KEGG KEGG entry

Clavaminate synthase (EC 1.14.11.21, clavaminate synthase 2, clavaminic acid synthase) is an enzyme with systematic name deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). This enzyme catalyses the following chemical reaction

(1) deoxyamidinoproclavaminate + 2-oxoglutarate + O₂ ⇌ amidinoproclavaminate + succinate + CO₂(2) proclavaminate + 2-oxoglutarate + O₂ ⇌ dihydroclavaminate + succinate + CO₂ + H₂O(3) dihydroclavaminate + 2-oxoglutarate + O₂ ⇌ clavaminate + succinate + CO₂ + H₂O

Clavaminate synthase contains nonheme iron.

References

Clavaminate synthase Wikipedia

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