Clapham is a surname. Notable people with the surname include:
Arthur Roy Clapham (1904–1990), British botanist
Jamie Clapham (born 1975), English soccer player
Sir John Clapham (economic historian) (1873–1946), British economic historian
John Clapham (historian and poet) (1566–1619), English historian and poet
John Greaves Clapham (c. 1796 – 1854 or later), Canadian business man and politician
Mark Clapham (born 1976), British writer
Michael Clapham (born 1943), UK politician, Labour Member of Parliament
Victor J. Clapham (South African Scout Association) Scouting notable, awardee of the Bronze Wolf in 1976
